There has been many questions regarding the safety of using the anti-emetic drug Zofran (ondansetron) on pregnant women to treat severe nausea and vomiting of pregnancy (NVP) also known as morning sickness, and hyperemesis gravidatrum. NVP typically occurs in 75% of pregnant women between the 4th and 14th week of gestation ranging from mild to severe.
NVP is believed to be a defensive mechanism of a mother’s body designed to protect the developing fetus from toxins. Most women get through the discomfort of the typical NVP symptoms with little long-term effects. However, untreated severe NVP and hyperemesis gravidatrum, which occurs in about 1% of all women, poses health dangers to both the mother and unborn child because of the resulting dehydration and electrolyte imbalance.
However, Zofran is not approved by the Food and Drug Administration (FDA) for such uses because of the lack of studies that show it is safe. There are some indications that women who take Zofran or any of its generic versions in their first trimester risk developmental problems for the fetus. Zofran is associated with adverse consequences to fetal development including congential heart disorders, cleft lip, cleft palate, club feet, abnormally shaped skull (craniosynostosis), and death. This is not a certainty, but women have a right to know that there is a risk.
Unfortunately, most physicians prescribing the medication are under the impression that it is safe for use by pregnant women. The drug’s manufacturer GlaxoSmithKline (GSK) did not inform them nor included it in the label that there is a possibility that Zofran can be dangerous to the fetus if it is taken prior to the 10th week of pregnancy. Moreoever, GSK actively encouraged doctors to prescribe the drug even though it is “off label” (not FDA approved).
According to the website of Williams Kherkher, if you were prescribed Zofran during the first trimester of your pregnancy and your child has birth defects mentioned above, you could be eligible for compensation. The failure to warn makes GSK potentially liable for civil damages. Consult with a Zofran lawyer in your area for more information about filing a Zofran lawsuit.
They do say that nothing ever surprises a New Yorker: they’ve seen it all before. But that’s in ultra-urbanized New York City; surely it is different in Westchester, where good schools and golf courses abound. But it turns out that it is far from the idyllic place it appears to be.
Westchester is known to be the site for several of the more brutal and heinous murders in the state and at least two suspected serial killers have made it their home at one point. Current news indicates that violent murder continues to happen, many considered “intimate” crimes as they involve close family members. There was one involving a psychologist for the New York Police Department and a murder-suicide involving a family of 4, two of whom were children. However, even if murder is in the air, it doesn’t mean that everything is as it appears.
Murder is considered the most serious of crimes anywhere, and New York is a death penalty state, which means that if convicted, a person charged with murder may be getting a needle in the arm. Because this is the ultimate punishment, getting a murder conviction is very difficult. The jury must be convinced that the defendant was guilty “beyond a reasonable doubt.” According to the website of the Law Offices of Richard A. Portale, P.C., a Westchester criminal defense lawyer need only introduce an element of doubt in the minds of the jury and that can result in an acquittal or at least a hung jury.
But there are instances when the evidence is circumstantial but compelling enough, the defendant unprepossessing enough, or both, to convince a jury that a defendant is guilty. It is important that when you are facing murder charges, you find a lawyer that has wide experience in handling murder cases and knows exactly what to expect and prepare for.
Benicar (Olmesartan Medoxomil) is antihypertensive medication developed by Japanese drug company Daiichi Sankyo and co-promoted in the US by Forest Laboratories which was approved for the US market in 2002 by the Food and Drug Administration (FDA). Olmesartan is part of a class of drugs known as angiotensin II receptor blockers (ARBs) or sartans, and has been uniquely and definitely linked as a causative factor in the development of condition known as sprue-like enteropathy, which mimics the symptoms of celiac disease.
Celiac disease (also known as celiac sprue) affects less than 1% of the US population and is characterized by the inability to properly digest gluten, a protein found in wheat and related grains. Over a period of time, symptoms of gastrointestinal (GI) disorder emerge including diarrhea, vomiting, and unintended weight loss which will eventually lead to permanent and irreversible damage to the small intestines called villous atrophy. The disorder is managed through a gluten-free diet.
Doctors were mystified when patients at the Mayo Clinic exhibited symptoms for celiac disease but were serologically negative for the disorder. They were put on a gluten-free diet but showed no improvement. However, when they were taken off Benicar, the symptoms stopped. The delayed action of Benicar contributed to the failure of doctors to immediately identify the drug as the causative factor. Findings for 22 patients were published in a 2012 issue of the journal Mayo Clinic Proceedings, calling the FDA’s attention to the problem. A review of Benicar was conducted and in July 2013, the FDA ordered the drug makers to include a warning of the risks of sprue-like enteropathy on the label.
The potential for harm from this negligence is quite extensive because it has been widely used since its introduction to the US market. More than 10 million prescriptions for Benicar were filled in 2012, many for long-time users to manage hypertension. A significant number of these patients who have suffered these mysterious symptoms are likely to file a Benicar lawsuit in the near future because they now have a reasonable idea of the cause of their injuries.
If you have suffered grievous injury from using Benicar, you may be eligible to get compensation. Consult with a competent dangerous drugs lawyer in your area to find out your legal rights and options.
It is entirely possible that W.C. Fields and Rudolf the red-nosed reindeer may have shared a common skin condition called rosacea. It commonly affects the areas of the nose and cheeks, and typically signaled by a tendency to blush or flush easily. So if you have not been a blushing bride for years, you could have rosacea.
Rosacea is a chronic skin condition that typically plagues 16 million adults in the US and is often mistaken for acne. It certainly flares at certain times just like acne, such as when the weather is hot, or there is a lot of stress. Rosacea manifests as small red bumps which may have cysts, pus, or eyes, and fine red lines in the skin.
It is not contagious, so most people just ignore it. In fact, a majority of the afflicted don’t even know they have the condition, which can be a problem later on. When it first starts out, it doesn’t look too bad, but the condition worsens if unmanaged and can be a source of embarrassment, especially if it affects the nose. A red, bulbous nose and puffy cheeks (rhinophyma) can be mistaken as signs of the habitual drunk, which is not good in so many levels, although rosacea can be aggravated by alcohol intake or eating spicy food.
In some cases, rosacea can cause problems by irritating the tissue lining of the eyes, and some experience eyelid redness and photosensitivity. This is called ocurlar rosacea and when left untreated can damage the patient’s sight.
While there is no known cure for rosacea, it is easily managed and controlled to keep it from progressing. Intense pulsed light (IPL) technology is one of the recommended protocols for some types of rosacea, but it must be administered in a reputable Auburn medical spa under the supervision of qualified professionals so as not to make the condition worse.
When SUVs were found to be more susceptible to rollover accidents, the Electronic Stability Control (ESC) was introduced by SUV manufacturers; this computer-based system was designed to detect skidding and the possibility of a rollover, and to automatically make the vehicle apply brakes to make sure that the driver does not lose vehicle control.
Last year, research and technology have helped giant car manufacturers to again come up with not one but two devices that will make driving much safer and U.S. roads more free more vehicular accidents, just as the National Highway Traffic Safety Administration (NHTSA) has and continues to envision.
These latest car technologies that are under tests are the Vehicle-to-Vehicle communication, or simply V2V and the V2I, which stands for “vehicle-to-infrastructure communication.” These devices, which the US government and car manufacturers are meticulously studying, are believed to reduce the number of road accidents by 81% (more than five million car accidents are recorded in the U.S. every year).
V2V, through the use of wireless signals, will enable cars to communicate with each, Information, such as other cars’ direction, speed and location, are provided by the device, allowing the driver to keep a safe distance from the other nearby or approaching vehicles, thus ensuring the avoidance of a possible collision.
The V2I, on the other hand, is designed to provide safety issues to the car and the driver by capturing information from traffic signals and road signs; it is also capable of abstracting information from the traffic management system on the best routes to take or information about the traffic.
Child support is always a tough issue that divorcing parents need to settle during their divorce process. All family law courts in the US consider the child’s best interest when dealing with child custody; child support is no exception. The BB Law Group PLLC, based in the Woodlands, Texas, states in an article posted on its website that child support agreements are designed in ways that will fully benefit the children affected by the divorce; the agreement, however, is made without compromising each of the spouse’s financial capabilities, needs and situations.
Child support is a monthly or regular financial payment, which the non-custodial parent, called the obligor, pays to the custodial parent (obligee) or the care-giver for the support of the child. This support payment is intended to cover the child’s basic needs, such as, food, clothing, shelter, education and health care. Child support is usually mandated by the court to the obligor until the child’s emancipation or 18th birthday; however, there can be instances when the court will require the obligor to continue providing financial assistance for the child’s future needs and activities, like college or advanced studies, vacation, camp activities and medical and/or dental needs.
The amount of financial support the non-custodial parent will be required pay will be decided by the court (if the spouses fail to arrive at an agreement) based on various factors, including the parent’s present income and their capability to pay, the needs of the child, the age and health of the spouses, the spouse’s professional opportunities and so forth. These factors are according to the stipulation of the Child Support Enforcement Act, a law that was passed in 1984 and which requires support of biological children.
If the amount of support was determined by the court, any intent to reduce or increase its amount should also be approved legally. Thus, any form of direct negotiation made by an obligor with the obligee to such effect, can result to contempt of court.
Family law issues, as stated in the website of Arenson & Maas, PLC in Cedar Rapids, are complicated and entail lots of complex legalities. Having a highly-qualified family law attorney can help couples address these legalities and arrive at a resolution that will be acceptable to both.
There are various and many concerns that need to be addressed by those thinking of starting a business –business and legal concerns. These include the specific service you intend your business to provide, profit and future development, business contracts, employment, salary and benefits of employees, business/commercial insurance, company policies, state and federal permits, license to operate, taxes, workplace safety standards and so forth.
Despite the importance of everything mentioned above, the two major items that will definitely have much impact on your business’ continuity and growth are salary and benefits of employees and business/commercial insurance. While competitive salary and great benefits will allow you to hire highly qualified applicants and keep them, the second will provide the necessary financial coverage to your company in the event of damage to anything connected to your firm’s operation.
As Raleigh workplace injury is a common incidence in any office setting, no matter how much employers adhere to the workplace safety standards mandated by state and federal laws (sometimes due to the carelessness or negligence of employees themselves), it is important that employers include in the employees’ benefits the Workers’ Compensation Insurance, which was made into law in 1908. This benefit is aimed at providing fast and sure financial assistance to employees who get injured while performing their job. It covers cost of medical treatment, loss of earnings due to inability of the employee to report to work, period of rehabilitation and death.
Commercial insurance, on the other hand, is necessary due to unexpected disasters or accidents that damage business properties or interrupt business operations that greatly affect the firm’s capacity to earn profits. Commercial insurance claims vary, depending on the coverage applied for by the firm. And, with regard to coverage, there are different policies, offered by insurance providers, meant to cover business owners’ specific needs. Some of these policies include:
- Standard Fire Insurance / Broad Named Peril Cover / Property All Risk Cover – which provides coverage of losses due to fire, lightning and so many other forms of damages
- Business Interruption Insurance – coverage for loss of revenue or profit due to interruption of business operations because of damage to insured property (so long as the cause of damage to insured property is included in the list of covered peril)
- Electronic Equipment Insurance (EEI) – while this policy is meant to cover data processing equipment, computers and all other electronic office equipment, it can also include coverage for business interruption
The effects of damage to business property can be extensive and serious, enough to reduce productivity and cause big losses in profit. After having invested time and money to keep your business running and competitive, it is just logical that you also make the necessary expenses which will provide protection to your investment.
While there are over 10 million individuals and families who own dogs in America, there is also close to a million reported incidences of dog bites and dog attacks each year. Dog bites and attacks are usually suffered by children, aged between five and nine, and older adults above 60 years old. The worst cases, however, are bites on the head or neck suffered by children aged four or younger.
A million dog bites each year is undeniably an alarming number, considering the fact that dogs are considered man’s best friend. Due to this, the US Centers for Disease Control and Prevention (CDC) has never ceased in advocating programs that give dog owners deeper and wider understanding about their pets and the proper way of taking care of these. There are private groups too which share vital information about certain breeds of dogs that are ideal in homes where there are children. This is due to the fact that a great majority of children-victims are not strangers, but either sons or daughter of the dog owners, and that certain breeds of dogs are just more hostile than others.
Some dog owners, who lack the time to take their dogs to their much needed walk or exercise, resort to hiring the services of dog walkers, to make sure that their pet’s energy is not transformed into, seemingly harmless, but actually, injurious playful moves or attacks.
When dogs bite or attack, there’s no telling what the extent of the injury is going to be. Some injuries are minor, resulting only to shallow scratches; but there are injuries that are quite serious, causing damage to nerves, disfigurement and paralysis, lacerations, infections or broken bones – besides the trauma and excessive fear instilled by the experience in children.
No matter how domesticated an owner would claim his/her dog is, there is never an assurance that such pet will not end up biting or attacking anyone. And, according to an article on the website of Ravid & Associates, P.C., negligent owners whose dogs bite or attack anyone should not be allowed to go unpunished.
When common medications fail to remedy vomiting sickness, heartburn (stomach pain or indigestion), gastroparesis and other gastrointestinal failures, doctors and other caregivers readily recommend Reglan, an oral drug approved by the FDA to treat post-surgery nausea, nausea due to chemotherapy, gastrointestinal disorders, and diabetic gastroparesis, which is a condition wherein the stomach fails to contract and empty.
Reglan, the brand name of metoclopramide, may be administered through injection or may be taken in liquid or pill form; it has been prescribed by doctors to patients since the late 1960s even for off-label use (not approved by the FDA), like morning sickness (experienced by pregnant women) and nausea and vomiting due to cluster headaches or migraine.
On February 26, 2009, manufacturers of Reglan were directed by the US Food and Drug Administration to display a Black Box warning (the most serious warning from the FDA which indicates the need to observe extra care if decision to take this drug is made) on the drug’s label. This is due to the proven connection of Reglan to the high risk of developing the neurological syndrome called tardive dyskinesia. This illness is characterized by repetitive, uncontrolled movements and its many symptoms include rapid movements of the trunk and extremities (arms and legs), rapid blinking of the eye, tongue protrusion, pursing and puckering lips, grimacing, and rapid finger movements that make the patient look like they are playing the piano or a guitar.
Tardive dyskinesia, sometimes, does not develop immediately, but over time, and the problem with those who develop this due to Reglan is that it usually persists indefinitely and does not cease even if use of the drug has long been stopped.
There are other reported Reglan side effects, such as convulsions or seizures, which are higher in epileptics using the drug, and symptoms linked to Parkinson’s disease. One serious complication caused by this drug is Neuroleptic Malignant Syndrome (NMS), which, in turn, causes unstable blood pressure, high fever, unconsciousness, muscular rigidity and even death. Despite the side-effects due to the use of the drug, immediate cessation of its use is never advisable also as this may result to other side effects.
It is a sad fact, as said in an article posted in the website of Habush Habush & Rottier S.C., that despite FDA monitoring, many harmful drugs still find their way into many stores. One major move Reglan users can resort to, in the hope of saving themselves from the dangers brought about by the drug, is complete cooperation and openness to their doctor about any symptoms of side-effects after starting to use it.
To millions of Americans, car is the basic means of transportation regardless of their destination. U.S. laws, however, strictly prohibit driving unless the person behind the wheel has been issued a driver’s license by his/her state’s Department of Motor Vehicles (DMV), also called Department of Public Safety or Registry of Motor Vehicles in other states. Before anyone can be issued a driver’s license, though, there are certain requirements and tests that need to be taken and passed. Requirements may vary from one state to another, but these usually include getting a Driver’s Manual from the DMV, taking a vision test, a written exam (on the rules of driving) and a road test.
The Driver’s Manual contains the rules and regulations of driving plus various photos, illustrating the different rules. The various processes involved before earning a driver’s license are intended to make sure that the applicant knows and will apply the rules when he/she is granted the right to drive his/her own car.
Stricter observance of road safety rules is probably more necessary today than in the past due to the rapid increase in the number of motor vehicles on the road, the heavier traffic and the increased speed limits in some major roads and highways – all these, with the very high number of road accidents every year, are enough to make anyone sometimes feel that the road is no longer as safe as it was before.
Today’s faster, yet more vulnerable-to-damage cars make accidents more dangerous, as these can cause greater destruction to property and more severe injuries to victims. According to the website of the Orange County lawyers at Seegmiller, the slightest driver error is often enough to cause a road accident. Sadly, many people don’t quite have a grip on which driving behaviors are most safe and are prone to errors and recklessness, leading to many accidents, injuries, and deaths.
The most common acts of driver recklessness, as identified by the National Highway Traffic Safety Administration (NHTSA), are tail-gaiting, driving over or below the speed limit, driving while intoxicated, failure to use signal lights, failure to stop on stop signs or slow down when making turns, abrupt lane changes and so forth.
NHTSA study also shows that those most guilty of driving recklessly are individuals between 15 and 24 years old. Unless caught, temporarily barred from driving, and corrected, these individuals will continue their reckless behavior on the road and continue putting others’ safety and lives at risk.
In the event of an accident, an injured victim has more than just injuries to worry about. Law firm Habush Habush & Rottier S.C. describes on its website the unexpected financial burden due to costly medical treatment and loss of income due to inability to report for work.
The fact is, car accidents are often preventable events; it merely requires responsible road behavior to be able to avoid the possibility of most accidents. One important thing to consider is, if you cannot or choose not to do away with your reckless driving behavior, then never drive – it’s that simple.